Condition-specific target prediction from motifs and expression

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چکیده

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Condition-specific target prediction from motifs and expression

MOTIVATION It is commonplace to predict targets of transcription factors (TFs) by sequence matching with their binding motifs. However, this ignores the particular condition of the cells. Gene expression data can provide condition-specific information, as is, e.g. exploited in Motif Enrichment Analysis. RESULTS Here, we introduce a novel tool named condition-specific target prediction (CSTP) ...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2014

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btu066